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doi: 10.1007/S11119-008-9082-0/METRICS 106 KumarL.ChhogyelN.GopalakrishnanT.HasanM

GCN2 inhibition sensitizes arginine-deprived hepatocellular carcinoma cells to senolytic treatment

3 , eaao4013 (2018)
The elevation of ROS within tumor cells has been associated with several detrimental effects, including enhanced cell proliferation, facilitation of mutations and heightened genetic instability (86)

The vast majority of them are well-known classical antioxidants, such as phenolic compounds able to scavenge toxic free radicals and mitigate oxidative stress-related cellular damage
