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Description
ACOX1 catalyzes the initial step of peroxisomal -oxidation and produces H 2 O 2 under O 2 consumption that contributes to the non-mitochondrial respiration rate ( pi must be interpreted with caution due to the discrepancy in sample size

Glob J Med Pharm Biomed Update 2022;17:10

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The authors reported a 30% increase in the molar yield of L-carnitine production (up to 56%) when using resting cells carrying this mutation [77]

More is not necessarily better, and extremely high doses are not required for effectiveness
