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Marginally, but not meaningfully

Duffy MJ, OGrady S, Tang M, Crown J (2021) MYC as a target for cancer treatment

Substances already found in the food supply are also generally considered fair game for inclusion in supplements

After evaluating the best candidate, we then showed that ES2 colocalized to FOXO4 foci and preferentially bound FOXO4 over TP53

However, there is good evidence that, although folic acid binds avidly to this receptor in the choroid plexus, it does not cross the opposite, apical membrane to enter the cerebrospinal fluid (CSF) (78)
