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Description
One of its principal targets is PARP, a nuclear enzyme involved in DNA repair and cellular stress responses

Metformin can interfere with the absorption of vitamin B12 in the small intestine, leading to lower B12 levels over time
Investigating vitamin B12 deficiency

1 Furthermore, the inhibition of NNMT by 5-Amino-1MQ impacts histone methylation, thereby modulating gene expression programs underlying metabolism and oncogenesis

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