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In the model of COPD established by exposure to CS, down-expression of GPX4 might ultimately induce iron accumulation and lipid peroxidation, which confirmed the key effect of ferroptosis on CS-induced COPD and further revealed the mechanism of iron accumulation inducing ferritinophagy mediated by NCOA4 in epithelial cells (81)
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Vascular endothelial cadherin (VE-cadherin): cloning and role in endothelial cell-cell adhesion
10.1016/j.apsb.2020.09.016
