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discovered that high sugar concentrations caused an increase in Smad4 expression in the mitochondria of podocytes

Lower concentrations are easier to dose accurately but require larger injection volumes per administration

[DOI] [PMC free article] [PubMed] [Google Scholar] Koch E.V., Bendas S., Nehlsen K., May T., Reichl S., Dietzel A

Tumor-associated macrophages (TAMs), which are infiltrating macrophages in tumor tissues, can be divided into M1-type macrophages that inhibit tumor growth and M2-type macrophages that promote tumor growth

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