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Sequencing studies were used to extend this system, and the mammalian GSTs active in drug metabolism are now classified into the alpha, mu and pi classes (Figure 1)

Conclusion The current understanding of the PPP suggests a complex regulatory control of the PPP and a role of this pathway beyond the provision of NADPH

To enable genetic associations to be interpreted in units of weight rather than BMI % , we also defined a corresponding weight phenotype, defined as the change in weight from baseline in kilograms

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Serum DAO levels have been proposed to be a marker of intestinal barrier integrity [85] and is elevated in Crohns disease [80]