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The authors concluded that TB4 is a multifunctional regenerative peptide important in dermal repair, acting through promotion of cell migration, stem cell mobilisation and differentiation, and inhibition of inflammation and apoptosis

Oxidative stress also activates inflammation via upregulation of NF-B , which promotes the transcription of inflammatory mediators, perpetuating a cycle of inflammation and ROS generation [25]

On this basis, the diagnostic criteria and treatment guidelines of the HRS were revised (Angeli et al., 2015)

This was attributed to the higher intracellular glutathione content in the #14 mutant when cultured in the molasses/CSL-based medium (2.6%), 87% higher than in the YP-based medium

Moreover, Vitamins C and E enhance each others therapeutic potential through their synergistic effects
