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[PubMed] [Google Scholar] 14.World Health Organization Expert Committee on Physical Status

Applications include investigating type 2 diabetes prevention, insulin resistance mechanisms, and novel therapeutic approaches for metabolic dysfunction through enzymatic pathway modulation

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Symptoms of real deficiency include fatigue, tingling or numbness in hands and feet, memory and concentration issues, mouth ulcers and pale skin, and a GP blood test is the only reliable way to confirm it