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Crazy thought but we also wondered if damp weather or rain might make this condition worse

Bacteria, dust, and skin oils can all degrade sensitive peptide chains
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Insulin binds on the red cell membrane and activates intracellular pathways, with an effect on erythrocyte deformability that was evidenced in several prior studies [28,148,149] and has been confirmed by more recent investigations [141]

[PubMed 20702066] 3110

Approximately 97% of IGF is bound
