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Depletion of NF2 and KIBRA in turn increases the nuclear levels of YAP/TAZ and promotes stemness and oncogenicity in hepatocellular carcinoma (Wang T

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Tumor risk via p53 pathway interference Mitigate risk by: Careful patient selection: exclude patients with pre-existing active malignancy or high tumour risk (e.g., known p53 mutations, familial cancer syndromes)

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