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Osteoarthritis The advent of ozone therapy modalities, specifically O 2 O 3 therapy and oxygenozone therapy (OOT), has significantly enriched the therapeutic spectrum for knee OA

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Proliferation The proliferative phase of healing is characterised by extensive activation of keratinocytes, fibroblasts, macrophages and endothelial cells, which orchestrate wound closure, matrix deposition and angiogenesis respectively

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