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Favorable social conditions can protect cardiovascular health, while upstream SDOH factors interact across domains to exert cumulative downstream effects on physiological and behavioral pathways (170)

Pharmacological mechanisms to increase POMC expression are not evident, due to the involvement of POMC-derived peptides in adrenal physiology [53]

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Sci Adv 9:eadh2858 de Miranda R, Cuthbert BJ, Klevorn T, Chao A, Mendoza J, Arbing M, Sieminski PJ, Papavinasasundaram K, Abdul-Hafiz S, Chan S et al (2023) Differentiating the roles of Mycobacterium tuberculosis substrate binding proteins, FecB and FecB2, in iron uptake