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Superoxide Dismutases and Superoxide Reductases

A clinical trial involving 42 PD patients (2:1 randomized to NAC or control) demonstrated that a 3-month NAC regimen (50 mg/kg intravenous weekly plus 600 mg oral twice daily, skipping oral doses on infusion days) significantly increased dopamine transporter binding compared with the control group

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In silico docking confirmed strong binding affinity of PDSE-derived rutin and quercetin with caspase-3, further supporting their role in apoptosis induction ( Mangifera pajang (a lesser-known mango species) kernel extract showed cytotoxicity in both hormone-dependent (MCF-7) and triple-negative (MDA-MB-231) BC cells, with IC50 values of 23 g/mL and 30.5 g/mL, respectively

Selenoprotein W controls epidermal growth factor receptor surface expression, activation and degradation via receptor ubiquitination
