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Functions as a for metabolic reaction required for synthesis of purines and pyrimidines: co-enzyme The reaction depends on methyl cobalamin as a co-factor and is also dependent on folate, in which the methyl group of methyltetrahydrofolate is transferred to homocysteine to form methionine and tetrahydrofolate

Currently, MOTS-c is only available as an injectable peptide

It mimics GH's lipolytic effects, promoting fat breakdown and inhibiting new fat formation, while early research suggests it preferentially acts on adipose tissue without significantly affecting IGF-1 or systemic GH levels

Methionine is a protein-based amino acid that helps your body release fatty proteins, inositol helps stimulate the removal of fat from the liver to prevent fat storage, and choline prevents cholesterol and fat build-up within your arteries

Efficacy and safety of once-weekly semaglutide monotherapy versus placebo in patients with type 2 diabetes (SUSTAIN 1): a double-blind, randomised, placebo-controlled, parallel-group, multinational, multicentre phase 3a trial