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On the other hand, we have found that EqASCEMS treated with SHBG are characterized by lower polarization of mitochondrial membrane which justified the enhanced proliferative ability of EqASCEMS when treated with SHBG

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In spite of these enzyme classifications, it is clear that cADPR is a second messenger that regulates intracellular calcium homeostasis in several cells (Figure 1) (24, 26, 27)

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