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This binding disrupts mitochondrial protein synthesis, which is essential for oxidative phosphorylation ( Structural studies using cryo-electron microscopy have mapped the binding sites of aminoglycosides on mitochondrial ribosomal subunits (Schacht et al., 2012

However, a number of limitations, such as safety concerns for different populations, unclear duration of positive changes, and difficult donor selection limit the clinical application [122]

Myalgic encephalomyelitis: A baffling syndrome with a tragic aftermath

doi: 10.3390/cancers13174287

The patient described here was negative for HBcAg liver staining, HBeAg, and HBV-DNA, leading to the assumption that most of the serum HBsAg originated from tumor cells and/or hepatocytes with HBV-DNA integration rather than from active infection