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Well, normally this vitamin is absorbed in the gut and so a disruption to normal gut function will reduce the amount of vitamin B12 that's being absorbed by the intestines and that will lead to a depletion of the normal body stores, which will then result in a deficiency in this vitamin within the body as a whole

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I lost count of the number of thyroid patients that Ive treated who were taking sublingual or oral B12 only to respond amazingly well to B12 injections
