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Conversely, the abundance of Prevotella significantly declines in patients with AIS, particularly those with LAA type stroke, as well as in individuals with IS
Still, a few risks deserve attention: Absolute contraindications: Wilson's disease or any other copper metabolism disorder, active cancer (because of GHK-Cu's pro-angiogenic activity), pregnancy, and breastfeeding

These transporters have a finite capacity that becomes saturated at higher doses, consequently causing absorption efficiency to decline sharply
Bicalho 2013

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