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Guchelar HJ, Hartog ME

Elbaz-Alon, Y

Drug diffusion through the brains extracellular space (ECS) is governed by cerebral blood flow, CSF dynamics, interstitial fluid movement, pH gradients, and extracellular matrix compositionwhile simultaneously constrained by therapeutic agents physicochemical properties including molecular size, surface charge, geometry, and molecular weight

10.1212/01.WNL.0000167411.93483.A1 101 JunejaM.ShamimU.JoshiA.MathurA.UppiliB.SairamS.et al (2018)

Scrolling on your phone, dealing with stress, or eating heavy meals during this period may reduce the quality of this critical recovery window