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10.3892/ol.2019.10564 145 YangX.HuangM.ZhangQ.ChenJ.LiJ.HanQ.et al (2021)

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Conducted experimental studies Study 3 Material The study used male albino rats weighing from 200g to 250g

IGF-1 , whose production is stimulated by GH, inhibits GH release in a biphasic manner: (1) by stimulating hypothalamic somatostatin release early, and (2) by inhibiting GH release after 24 hours, probably by inhibiting GH mRNA transcription (451,452)
