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The site of the macrocyclization was determined by cleaving the cyclic peptides ( 2u and 2u ) and ( 2v and 2v ) at Met using CNBr, and the resulting fragments were analyzed by HRMS (Supplementary Fig
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Brain 141 , 357364 (2018)

and with a power density of 37.5 mW/cm 2 PW (100 Hz, 4.5 J/cm 2 ), where an increase of 157% in cortical ATP was observed
