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Findings here Stress B12 can also be depleted in times of stress.This occurs from a range of mechanisms

Here's the breakdown: Alcohol (ethanol) gets converted by your liver into acetaldehyde, a compound that's significantly more toxic than alcohol itself

Anionic lipids drastically accelerate aggregation, an effect that is substantially weaker for sphingophospholipid and zwitterionic phospholipids (Sitton et al., 2025)

Int J Mol Sci (2018) 19(4):1232

In Lebers hereditary optic neuritis contraindication, B12 can cause blindness