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ALC was more effective at doses higher than 2000 mg/d than at doses lower than 1500 mg/d
and these are both further subcategorized by origin or associated syndromes, among other factors [219]
Heidt et al., 2023)
Clin Sci
Chronobiology reframes therapeutic timing: administering C-C chemokine receptor 2 (CCR2) antagonists aligned with circadian rhythms of immune cell trafficking could enhance efficacy while respecting individual sleep-wake cycles, critical for patients whose work schedules disrupt circadian alignment [249]
