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"In this study, lower vitamin B12 levels were associated with adverse lipid profiles, higher AIP, and elevated blood pressure, highlighting the potential role of vitamin B12 in cardiovascular health," the study found

In these cases, high B12 is not causing the liver damage

B12 Nasal Gel Taking B12 nasal gel for malabsorption (pernicious anemia) can cause some of the same side effects as B12 injections

However, due to rare but serious adverse effects (e.g., thrombocytopenia, cardiac arrhythmias, hypersensitivity reactions), many guidelines recommend against routine use

If youre an endurance athlete, follow a plant-based diet, or experience unexplained fatigue, B12 testing makes sense