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Additionally, renal damage from CaOx crystal deposition may hinder uric acid excretion, culminating in hyperuricemia 42,43

Sorafenib-induced hepatocellular carcinoma cell death depends on reactive oxygen species production in vitro and in vivo
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It binds to HGF with high affinity (Kd = 65 pM) and markedly augments the capacity of HGF to activate c-Met phosphorylation, even at subthreshold concentrations of the growth factor
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