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Peralta MF, Guzmn ML, Prez AP, Apezteguia GA, Frmica ML, Romero EL, et al

The hepatic GSH transport in ER has been investigated and a bi-directional, saturable GSH transport was found in rat liver microsomal vesicles

Although randomized studies have not shown an overall effect on the frequency of exacerbations, a post-hoc analysis of a clinical trial reported a decrease in their severity (87) Overall, these results demonstrate that A1PI augmentation therapy offers significant benefits in slowing the progression of emphysema and improving clinical outcomes for patients with AATD, underscoring the importance of timely and continuous treatment

[DOI] [PubMed] [Google Scholar] 50.Ottersen O.P., Storm-Mathisen J., Laake J.H

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