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Glutathione, glutathione-related enzymes, and oxidative stress in individuals with subacute occupational exposure to lead

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The findings contribute to a broader understanding of how indole-based small molecules interact with hp GSTP1-1 and may serve as a starting point for future studies exploring structurally optimized derivatives or other indole-containing metabolites with enhanced inhibitory potential

First-in-human phase i study of a next-generation, oral, TGF receptor 1 inhibitor, LY3200882, in patients with advanced cancer

In H358 sgChr19-SAFE control cells, but not H358 sgNQO1 cells, LCS3 induces an increase in NADPH, further suggesting that the cellular effects of LCS3 are inhibited upon knockout of NQO1 (Supplemental Fig