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In a phase 2 trial of 114 patients with moderately elevated TG levels (200500mg/dL), treatment with olezarsen resulted in mean TG reductions of 23% at 10 mg every 4 weeks, 56% at 15 mg every 2 weeks, 60% at 10 mg weekly, and 60% at 50 mg every 4 weeks, compared with a 6% increase in the pooled placebo group.38 Significant decreases in apo-CIII, VLDL, non-HDL-C, and apo B were also observed

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