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Compared with the model group, the high-dose group (100 g/mL), low-dose group (10 g/mL), and positive control group (lidocaine, 100 g/mL) all showed significant reductions in HR and QRS (P 20% was invalid

The enzyme methylmalonyl-CoA mutase also requires B12 and so a homocysteinuria resulting from a deficiency in this vitamin is also associated with methylmalonic acidemia

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