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Transgenic = 5xFAD

Using synthetic and natural anti-inflammatories may be another alternative to supress over functioning of neutrophils and NETs formation

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By downregulating NF-B and increasing Nrf2 activation, the entkauranoid diterpenoid glaucocalyxin-B, which is produced from Rabdosia japonica, was demonstrated to decrease oxidative stress and inflammation in a PD rat model caused by LPS [119]

Curcumin derived from medicinal homologous foods: its main signals in immunoregulation of oxidative stress, inflammation, and apoptosis