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Among the proteins activated by NRF2 are SOD, haem oxygenase-1 (HO-1), involved in the defense system against OS, and -glutamyl cysteine synthetase (-GCS), a rate-limiting enzyme in glutathione biosynthesis

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doi: 10.1073/pnas.1120210109

Side Effects and Safety Considerations Both CoQ10 and L-carnitine are generally well-tolerated when used at recommended doses, though certain side effects and safety considerations warrant attention
[DOI] [PubMed] [Google Scholar] 4.Kim J, Park J, Lim K
