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In light of this, high-dose IVC has re-emerged as a potent anti-cancer agent over the past two decades, with several phase I and a few phase II clinical trials reporting high tolerability and safety with promising signs of efficacy in the treatment of various cancer types, either as monotherapy or as a combination therapy [1416]

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PH performed the statistical analysis

Oral versus intramuscular cobalamin treatment in megaloblastic anemia: a singlecenter, prospective, randomized, openlabel study

This enzyme converts glutamine into glutamate, which is then used for both ATP production through the citric acid cycle or glutathione synthesis, ultimately supporting cell proliferation and maintaining ROS homeostasis [174]
