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IGF-1 LR3 functions as a potent, long-acting agonist of the IGF-1 Receptor (IGF-1R) , activating key intracellular signaling pathways, primarily the PI3K Akt and MAPK pathways

Oral administration of SFN after CCl 4 significantly decreased serum ALT in mice and reduced necrotic zones and lipid peroxidation in the liver ( 4 in mice was also ameliorated by SFN treatment, possibly through Nrf2-mediated antioxidation and enhanced acetaldehyde metabolism (Ishida et al., 2021)

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Aging 34 , 15641580 (2013)

Updated perspectives on the contribution of the microbiome to the pathogenesis of mucositis using the MASCC/ISOO framework