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The recently reported roles of GSH in defending cells against oxidative stress and its involvement in protein modification and cellular signaling highlight the importance of the maintenance of intracellular GSH for cellular function and viability [48,49]
In hepatic stellate cells, these exosomes induce increased integrin -5 and 8, Smad-3, TIMP-1 and 4 , and matrix metalloproteinase-9 ( MMP-9 ) expression
