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Experimental studies suggest that targeting these chaperones, or their associated kinase CSK2, could be a novel strategy to reduce platelet dysfunction and cardiovascular risk in diabetic patients (Hernndez Vera et al., 2012)

Decrease in frataxin levels also caused downregulation of heme synthesis enzymes, iron export proteins and iron storage proteins, demonstrating its importanceand the importance of Fe-S assembly as a regulatory node by which iron availability regulates heme synthesis (Huang et al., 2009)

the difference was statistically significant between both sides of the face ( P value of 0.001) (Table 2)

The survival rate of S-3/pKLH167, S-3/pKLH337, S-3/pKLH341, and S-3/pKLH344 were 73, 90, 83, and 81%, respectively, which were higher than that of wild-type (55%) under 3.5 mmol/L H 2 O 2 (Figure 4C)