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Cureus 16 , e68639 (2024)
Prostaglandins, Leukotrienes, and Essential Fatty Acids, 65 (1), 17
Davis RJ
However, hit fragments have a higher ligand efficiency per atom, when compared to drug-like compounds, being good starting points for drug discovery (Hubbard & Murray, 2011)
Of note, mismatch repair deficient tumours, usually resistant to ICI, showed a very effective response when combined with high-dose VitC
