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Our in vitro studies have uncovered for the first time the ability of TNBS, a heterocyclic agent, to directly interact with the nucleophilic antioxidant, GSH, in a non-enzymatic fashion resulting in its almost instantaneous disappearance from the medium

Lactate metabolism and its role in the brain Under normal physiological conditions, glucose is converted to pyruvate in the cytoplasm and subsequently enters the tricarboxylic acid (TCA) cycle in the mitochondria, producing substantial energy, oxygen, and water for cellular activities

although their phagocytic activity and release of neutrophil extracellular traps (NETs) contribute to pathogen clearance, excessive activation and dysregulated NET formation cause direct tissue injury (Long et al., 2024)