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There are two ways alcohol can increase histamine: The DAO enzyme, which breaks down histamine, is inhibited by alcohol .[ref] Additionally, both alcohol and acetaldehyde can trigger mast cells and basophils to release histamine in the periphery

[DOI] [PMC free article] [PubMed] [Google Scholar] 16.National Institute for Health Care Excellence (NICE) Vitamin B12 Deficiency in over 16s: Diagnosis and Management (NG239) [(accessed on 6 March 2024)]

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