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The introduction of GOx is another strategy for the development of glucose-responsive materials, as GOx catalyzes the conversion of glucose into gluconic acid, which generates electrostatic repulsions through protonation and causes the matrix to swell, thereby facilitating drug release [327, 328]

Once all bacteriostatic water is added, withdraw the needle

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The complex I and complex III of ETC are able to produce the superoxide anion radical (O 2 ) and release it to both the matrix and the intermembrane space