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This paper provides an extensive review of the cellular properties of CS cells in culture, including their sensitivity to DNA-damaging agents, repair deficiencies and protein interactions

These replicative processes imply a highest rate of mitochondrial oxygen consumption and reactive oxygen species (ROS) generation
In studies involving inflammatory bowel disease (IBD), the peptide has been shown to mitigate intestinal inflammation, reduce lesion size, and promote the regeneration of the epithelial lining

doi: 10.1016/j.jacc.2008.06.019