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In diet-induced obese (DIO) mouse models, NNMT inhibition with 5-Amino-1MQ was associated with reduced white adipose tissue mass without affecting food intake, suggesting changes in energy expenditure rather than appetite suppression
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Vit B12 and synucleinopathy A recent study demonstrated that Vit B12 effectively impedes the formation of SN fibrils in a manner dependent on dosage in-vitro experiments
