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Fisetin acts as an antioxidant through multiple mechanisms, by scavenging ROS/RNS (reactive nitrogen species), restraining oxidant enzymes, alleviation of oxidative stress induced by nitric oxide, reinforcing enzymatic and non-enzymatic intracellular antioxidants, chelating with transitional metal ions, acting as a substrate for oxidoreductase activity, and interaction with redox-related signaling pathways [67]

The neural substrates of memory systems impairment in Alzheimers disease

While the Warburg effect is a hallmark of cancer metabolism, recent studies have identified other metabolic features, including metabolic symbiosis, glutamine metabolism, and the reverse Warburg effect, wherein CAFs in the tumor stroma cause autophagy and glycolysis to produce lactate (4346)

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& Zinger, S