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Clinical Implications Based on Extraction Ratio 15 High-Extraction Drugs (High E): These drugs, by definition, have a low oral bioavailability (F is low)
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When illnesses hinder their abilities, the repercussions are significant
A daily supplement providing 150 g of iodine, as recommended by the American Thyroid Association (158), will help to ensure that US breastfeeding women consume sufficient iodine during these critical periods
