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However, elevated levels of ROS, as observed in pathologic pregnancies, are associated with adverse outcomes, including tissue and mitochondrial damage and accelerated aging

The effects of increased intracellular H 2 O 2 availability appear to be quite specific to glutathione, and do not involve readily detectable changes in the status of other major antioxidants or redox couples (Mhamdi et al., 2010a)

Preclinical studies have shown a favorable safety profile, but more rigorous clinical trials are necessary to fully understand its potential side effects and risks

Glutathione transferases: A structural perspective