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Description
Meanwhile, PLIN1 predominates and envelops large LDs in macrophages, resulting in the downregulation of lipid efflux proteins ATP-binding cassette transporter A Member 1 (ABCA1) and ATP Binding Cassette Subfamily G Member 1 (ABCG1), a critical process for constraining the development of macrophage inflammatory phenotype and providing protection against atherosclerotic lesions [35]
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In view of the important biological activities that have already been demonstrated for such aldehydes, it is important to know the mechanisms of their formation
