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wrap vials in foil or store in an opaque container [9]

Heterogeneity in NMA was high (between-study variance=5.75, I 2 =96%) compared also to the Rhodes et al 22 empirical distribution (median 0.05, 95% range: 0.00 7.56)

This is consistent with research on adaptive thermogenesis the well-recognised reduction in heat production that accompanies calorie restriction and weight loss more broadly and is not unique to retatrutide