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Gastroenterology , 145 (2), 416-25.e1-4 Opitz, C

J., Grimes, P

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For the reversal of cytotoxicity assays, a constant non-toxic concentration of either plumbagin (0.5 M) or vitamin K3 (1 M) was added with varying concentrations of mitoxantrone and the extent of reversal was calculated based on the changes in the relative resistance values which were derived by dividing the IC 50 value of the resistant cells by the IC 50 value of the sensitive control cells

237 These findings suggest that the complex interactions between copper and ferroptosis merit further investigation
