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Mother turned out to have pernicious anemia with a serum B12 of 96 pmol/l

## Combining Semaglutide with Supportive Therapies One advantage of transitioning from AOD-9604 to a GLP-1 **weight loss peptide** is the ability to complement the protocol with well-studied supportive therapies: ### NAD+ for Metabolic and Anti-Aging Support [NAD+ injections](/guides/nad-injection-benefits-anti-aging-energy-recovery-guide) support mitochondrial function, cellular energy production, and DNA repair all of which may be beneficial during active **fat loss**

By blocking the activity of NNMT, 5-Amino-1MQ increases the bioavailability of nicotinamide, a precursor to NAD+, thereby elevating intracellular NAD+ levels

However, the metabolic enhancement 5-amino-1mq provides may make a given caloric deficit more effective, meaning faster results without more extreme restriction

Certain populations, including older adults and people following a vegan diet, are at a higher risk of vitamin B12 deficiencies and may benefit from taking a vitamin B12 supplement