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A study showed that people with diabetic neuropathy got better symptoms with regular B12 shots
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Therefore, the methylation of NA is not only relevant to the abundance of free NAD + but is also relevant to the activity of these NAD + -consuming enzymes, because as a metabolite of these NAD + -consuming reactions, NA naturally has inhibitive effects on these enzymes
At the same time, the production of red blood cells is also disrupted and it is this combined lack that makes severe B12 deficiency so debilitating, elaborates Dr
